Fatty acid profile of erythrocyte membranes as possible biomarker of longevity.

@article{Puca2008FattyAP,
  title={Fatty acid profile of erythrocyte membranes as possible biomarker of longevity.},
  author={Annibale A. Puca and Peter Andrew and Valeria Novelli and Chiara Viviani Anselmi and Francesco Somalvico and Nicola Cirillo and Chryssostomos Chatgilialoglu and Carla Ferreri},
  journal={Rejuvenation research},
  year={2008},
  volume={11 1},
  pages={63-72}
}
Offspring of long-lived individuals are a useful model to discover biomarkers of longevity. The lipid composition of erythrocyte membranes from 41 nonagenarian offspring was compared with 30 matched controls. Genetic loci were also tested in 280 centenarians and 280 controls to verify a potential genetic predisposition in determining unique lipid profile. Gas chromatography was employed to determine fatty acid composition, and genotyping was performed using Taqman assays. Outcomes were measured… CONTINUE READING