Fatty acid metabolism in pulmonary arterial hypertension: role in right ventricular dysfunction and hypertrophy.

@article{Talati2015FattyAM,
  title={Fatty acid metabolism in pulmonary arterial hypertension: role in right ventricular dysfunction and hypertrophy.},
  author={Megha H Talati and Anna R Hemnes},
  journal={Pulmonary circulation},
  year={2015},
  volume={5 2},
  pages={
          269-78
        }
}
Pulmonary arterial hypertension (PAH) is a complex, multifactorial disease in which an increase in pulmonary vascular resistance leads to increased afterload on the right ventricle (RV), causing right heart failure and death. Our understanding of the pathophysiology of RV dysfunction in PAH is limited but is constantly improving. Increasing evidence suggests that in PAH RV dysfunction is associated with various components of metabolic syndrome, such as insulin resistance, hyperglycemia, and… CONTINUE READING
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Magnetic resonance imaging analysis of right ventricular pressure-volume loops: in vivo validation and clinical application in patients with pulmonary hypertension

  • T Kuehne, S Yilmaz, P Steendijk
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