Fatty acid-mediated effects on the glutathione redox cycle in cultured endothelial cells.

@article{Toborek1994FattyAE,
  title={Fatty acid-mediated effects on the glutathione redox cycle in cultured endothelial cells.},
  author={Michal Toborek and Bernhard Hennig},
  journal={The American journal of clinical nutrition},
  year={1994},
  volume={59 1},
  pages={60-5}
}
Endothelial barrier dysfunction after exposure to fatty acids may be mediated by disturbances in antioxidant protection. To evaluate this hypothesis, components of the glutathione redox cycle such as total, reduced, and oxidized glutathione and glutathione reductase and peroxidase were measured in cultured porcine endothelial cells exposed to 90 mumol/L of stearic acid (18:0), oleic acid (18:1 omega-9), linoleic acid (18:2 omega-6), linolenic acid (18:3 omega-3), and/or buthionine sulfoximine… CONTINUE READING

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