Fatty acid incorporation in endothelial cells and effects on endothelial nitric oxide synthase

  title={Fatty acid incorporation in endothelial cells and effects on endothelial nitric oxide synthase},
  author={S. Couloubaly and C. Delom{\'e}nie and D. Rousseau and J. L. Paul and A. Grynberg and M. Pourci},
  journal={European Journal of Clinical Investigation},
  • S. Couloubaly, C. Deloménie, +3 authors M. Pourci
  • Published 2007
  • Biology, Medicine
  • European Journal of Clinical Investigation
  • Background  The nature of fatty acids provided by the diet as well as plasma lipid metabolism can modify the composition and properties of plasma membrane and thus the activity of membrane proteins. In humans, as well as in experimental models, diabetes is associated with both an alteration in serum lipid profile and a documented endothelial dysfunction. This in vitro study investigated on an immortalized human endothelial cell line (EA.hy 926) the specific effects of several free fatty acids… CONTINUE READING
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