Fatty acid composition of low-density lipoprotein influences its susceptibility to autoxidation.

@article{Thomas1994FattyAC,
  title={Fatty acid composition of low-density lipoprotein influences its susceptibility to autoxidation.},
  author={Michael J K Thomas and T M Thornburg and James Manning and Kathy Hooper and Lawrence Lee Rudel},
  journal={Biochemistry},
  year={1994},
  volume={33 7},
  pages={1828-34}
}
Low-density lipoprotein (LDL) oxidation was studied using copper or the water-soluble initiator azobis(2-amidinopropane) dihydrochloride (ABAP) to catalyze the reaction. These studies were carried out with purified, native LDLs that had a well-defined composition and which contained different concentrations of polyunsaturated fatty acids (PUFA) and alpha-tocopherol. The LDL was obtained from nonhuman primates fed diets enriched in cholesterol and one of four types of fatty acids: saturated (Sat… CONTINUE READING
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