Fatty acid bile acid conjugates inhibit atherosclerosis in the C57BL/6 mouse model.

OBJECTIVE The aim of the current research was to study whether fatty acid bile acid conjugates (FABACs) have a beneficial effect on atherosclerosis progression and blood lipid levels in mice. METHODS C57BL/6 female mice, fed a high-fat Paigen diet, were administered an oral dose of FABAC or DDH2O daily. Quantification of atherosclerotic fatty-streak… (More)