Fatty Acid Composition of Human Brain Sphingomyelins: Normal Variation with Age and Changes during Myelin Disorders.


Sphingomyelins have been isolated in almost quantitative yield from normal and pathological human nervous tissues, and their fatty acid compositions determined by gas-liquid chromatography. In normal frontal lobe the proportion of stearic acid (18:O) decreases with increasing age from about 80% in the newborn to about 40% in the adult, whereas the C ~ Z C… (More)


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