Fatigue of inspiratory muscles and their synergic behavior.

  title={Fatigue of inspiratory muscles and their synergic behavior.},
  author={Ch. Roussos and M S Fixley and David Gross and Peter T. Macklem},
  journal={Journal of applied physiology: respiratory, environmental and exercise physiology},
  volume={46 5},
The time (tlim) required to produce inspiratory muscle fatigue was measured in five normal subjects breathing at functional residual capacity (FRC) against a variety of high inspiratory resistive loads. In every breathing test the subjects generated with each inspiration a mouth pressure (Pm) that was a predetermined fraction of maximum Pm (Pmmax). They continued breathing until they were unable to generate this Pm. The Pm/Pmmax that could be generated indefinitely (Pmcrit) was around 60%. The… CONTINUE READING


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