Fatigue in sarcoidosis: a systematic review

@article{Kleijn2009FatigueIS,
  title={Fatigue in sarcoidosis: a systematic review},
  author={W. D. de Kleijn and J. de Vries and E. Lower and Marjon Elfferich and R. Baughman and M. Drent},
  journal={Current Opinion in Pulmonary Medicine},
  year={2009},
  volume={15},
  pages={499–506}
}
Purpose of review Several studies have investigated fatigue among sarcoidosis patients. The purpose of this review is to analyze published data on the assessment, prevalence, etiology, and treatment of sarcoidosis-associated fatigue. Recent findings Fatigue was identified as a prominent problem in sarcoidosis, and its presence was frequently associated with impaired quality of life, compared with patients without fatigue. Although the studies with good methodological fatigue assessment found no… Expand
Factors Associated With Fatigue in Sarcoidosis
TLDR
It is important to consider that multiple clinical factors, especially comorbidities, contribute to the high degrees of fatigue in sarcoidosis. Expand
Types of fatigue in sarcoidosis patients.
TLDR
Careful consideration to categorize patients with sarcoidosis in the three types of fatigue will help healthcare providers to understand the challenges these patients encounter, especially for those with All Day Fatigue. Expand
Sarcoidosis-associated fatigue
TLDR
Despite an exhaustive search for treatable clinical causes of fatigue, most patients’ complaints of fatigue are not correlated with clinical parameters of disease activity, so there is a need for studies evaluating the causes and new therapeutic options of sarcoidosis-associated fatigue. Expand
Fatigue in sarcoidosis: incompletely understood, inadequately treated
  • O. Sharma
  • Medicine
  • Current opinion in pulmonary medicine
  • 2012
TLDR
Female patients were more affected by fatigue than male patients and, compared with the general population, young sarcoidosis patients were especially affected by fatiguing, suggesting that fatigue in association with a systemic illness can be ominous. Expand
Fatigue in patients with sarcoidosis, compared with the general population.
TLDR
Compared with the general population, young sarcoidosis patients are especially affected by fatigue, and the comparison to norm data is highly recommended for the evaluation of age and gender differences. Expand
Assessment of Fatigue and Other Extra-Pulmonary Manifestations in Patients Diagnosed with Sarcoidosis: A Prospective Observational study in a South Indian Tertiary Care Centre
TLDR
This study reiterates the importance of fatigue as a predominant symptom in patients with sarcoidosis which may be ignored in the clinical setting and identifies therapies which may help patients in treating this symptom. Expand
Characterization of chronic fatigue in patients with sarcoidosis in clinical remission.
TLDR
Fatigue in patients with sarcoidosis in clinical remission is a frequent symptom and can be characterized as a severe and long-lasting problem, symptomatically similar to chronic fatigue syndrome. Expand
Fatigue in sarcoidosis and idiopathic pulmonary fibrosis: differences in character and severity between diseases.
TLDR
The fatigue experienced by the two groups appears to be different; sarcoidosis patients report greater frequency of mental fatigue whereas IPF patients appear to suffer exhaustion, potentially related to dyspnoea. Expand
Nature of fatigue moderates depressive symptoms and anxiety in sarcoidosis.
TLDR
It is shown that fatigue is often accompanied by depressive symptoms and anxiety, although these symptoms are not fully overlapping, which indicates that patients with All Day Fatigue may benefit from psychological interventions in the management of fatigue. Expand
Psychological stress in sarcoidosis
  • M. Wilsher
  • Medicine
  • Current opinion in pulmonary medicine
  • 2012
TLDR
Understanding the global impact of sarcoidosis is important for patients and clinicians, and use of validated instruments allows for more comprehensive assessment of the disease and the impact of any interventions. Expand
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TLDR
If these results were to be replicated in a prospective study, fatigue as measured by the FAS could be a good indicator of QOL in sarcoidosis patients. Expand
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TLDR
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TLDR
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