Fatigue in multiple sclerosis: relation to depression, physical impairment, personality and action control.

@article{Penner2007FatigueIM,
  title={Fatigue in multiple sclerosis: relation to depression, physical impairment, personality and action control.},
  author={Iris Katharina Penner and Nina Bechtel and Carla Raselli and Markus Karl St{\"o}cklin and Klaus Opwis and Ludwig Kappos and Pasquale Calabrese},
  journal={Multiple sclerosis},
  year={2007},
  volume={13 9},
  pages={1161-7}
}
Although fatigue is one of the most common symptoms of multiple sclerosis, it is yet poorly understood and therefore difficult to manage. To clarify the nature of fatigue we investigated its relationship to depression, physical impairment, personality and action control and compared these variables between a sample of 41 MS patients and 41 healthy controls. Physical impairment was assessed by the EDSS and all other dimensions, using questionnaires. Stepwise linear regression analyses revealed… CONTINUE READING