Fatigue favors in vitro Th1 and Th17-like cell expansion and reduces corticoid sensitivity in MS patients.

@article{AlvarengaFilho2017FatigueFI,
  title={Fatigue favors in vitro Th1 and Th17-like cell expansion and reduces corticoid sensitivity in MS patients.},
  author={H{\'e}lcio Alvarenga-Filho and Marisa Salles and Joana Hygino and Thais B. Ferreira and Priscila M Sacramento and Clarice Monteiro and Cl{\'a}udia Cristina Ferreira Vasconcelos and Regina Maria de Papais Alvarenga and Cleonice A M Bento},
  journal={Journal of neuroimmunology},
  year={2017},
  volume={303},
  pages={81-89}
}
Fatigue is a common "ghost" symptom in patients with multiple sclerosis (MS), an autoimmune disease mediated by T cells that target myelin antigens of the central nervous system. As fatigue has been associated with inflammatory states, its occurrence may negatively impact MS progression. The aim of this study was to evaluate the impact of fatigue on the cytokine profile of patients with relapsing-remitting (RR) MS. For our study, blood were collected from MS patients in clinical remission phase… CONTINUE READING