Fate restriction and multipotency in retinal stem cells.

@article{Centanin2011FateRA,
  title={Fate restriction and multipotency in retinal stem cells.},
  author={L{\'a}zaro Centanin and Burkhard Hoeckendorf and Joachim Wittbrodt},
  journal={Cell stem cell},
  year={2011},
  volume={9 6},
  pages={553-62}
}
Stem cells have the capacity to both self-renew and generate postmitotic cells. Long-term tracking of individual clones in their natural environment constitutes the ultimate way to validate postembryonic stem cells. We identify retinal stem cells (RSCs) using the spatiotemporal organization of the fish retina and follow the complete offspring of a single cell during the postnatal life. RSCs generate two tissues of the adult fish retina, the neural retina (NR) and the retinal-pigmented… CONTINUE READING
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