Fate of indium 111-labeled platelets during cardiopulmonary bypass performed with membrane and bubble oxygenators.

@article{Peterson1982FateOI,
  title={Fate of indium 111-labeled platelets during cardiopulmonary bypass performed with membrane and bubble oxygenators.},
  author={Keith A. Peterson and Mrinal K. Dewanjee and M P Kaye},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={1982},
  volume={84 1},
  pages={39-43}
}
To elucidate the effects of bubble and membrane oxygenators on platelet integrity, we developed a quantitative method of determining platelet lysis during cardiopulmonary bypass. Two groups of dogs whose platelets had been labeled with indium 111 were subjected to 1 hour of cardiopulmonary bypass. In Group A (bubble oxygenator), platelet lysis as measured by free plasma 111In levels increased from 6% +/- 1% to 33% +/- 7% during bypass. In Group B (membrane oxygenator), plasma 111In levels… CONTINUE READING
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