Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste.

  title={Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste.},
  author={Joanne C Chee-Sanford and Roderick Ian Mackie and Satoshi Koike and Ivan G. Krapac and Yu-Feng Lin and Anthony C. Yannarell and Scott Maxwell and Rustam I. Aminov},
  journal={Journal of environmental quality},
  volume={38 3},
Antibiotics are used in animal livestock production for therapeutic treatment of disease and at subtherapeutic levels for growth promotion and improvement of feed efficiency. It is estimated that approximately 75% of antibiotics are not absorbed by animals and are excreted in waste. Antibiotic resistance selection occurs among gastrointestinal bacteria, which are also excreted in manure and stored in waste holding systems. Land application of animal waste is a common disposal method used in the… 

Figures and Tables from this paper

Antibiotics and Antibiotic Resistance Genes in Animal Manure – Consequences of Its Application in Agriculture

A broader view is taken than previous studies of this topic, discussing recent data on antibiotic use in farm animals and the effect of these practices on the composition of animal manure, and how fertilization with animal manure may alter soil and crop microbiomes, and proposes the drivers of such changes and their consequences for human health.

Monitoring of Antibiotics and Antibiotic Resistance Genes in Agroecosystems

This chapter discusses the assembly of work that concentrates on aspects of the fate, transport, and persistence of antibiotics and antibiotic resistance genes in the innate environments with emphasis on culture and molecular-based methods and mechanisms relevant to the soil environments.

Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events

Man manure shows unique features as a hotspot for antimicrobial gene dissemination by horizontal transfer events: richness in nutrients, a high abundance and diversity of bacteria populations and antibiotic residues that may exert a selective pressure on bacteria and trigger gene mobilization; reduction methodologies are able to reduce the concentrations of some, but not all, antimicrobials and microorganisms.

Antibiotic residues and resistance in the environment

More research is needed into the relationship between the concentrations of antibiotic residues in the environment and the prevalence and persistence of environmental antibiotic resistance, and the fate of antibiotics in the main reservoirs should be studied, including antimicrobially active metabolites and their bioavailability.

Fertilizing with Animal Manure Disseminates Antibiotic Resistance Genes to the Farm Environment.

This study shows that antibiotic resistance genes are disseminated on Finnish production animal farms, and the spreading of resistance genes in farm-associated environments could possibly be limited by experimenting with new manure handling methods that could reduce the abundance of the genes in manure used for land application.

Animal waste antibiotic residues and resistance genes: A review

Abstract Antibiotic resistance is an emerging risk for human and animal health, and mitigating the risk requires an improved understanding of various sources of risks and identifying the level of

Fate of Antibiotics and Antibiotic Resistance during Digestion and Composting: A Review.

Current literature on the fate of antibiotics, ARB, and antibiotic resistance genes (ARGs) during anaerobic digestion and composting of manure and wastewater residuals demonstrates that composting significantly reduces levels of extractable antibiotics in livestock manure in nearly all cases.

Antimicrobial Resistance Arising from Food-Animal Productions and Its Mitigation

This chapter discusses the development and occurrence of antimicrobial resistance arising from food animal production, as well as strategies and technologies to mitigate dissemination of AMR off farms to broad environment.



Occurrence and reservoirs of antibiotic resistance genes in the environment

There is clear evidence that the self-resistance genes found within antibiotic gene clusters of the producers have transferred to other non-producing bacteria, and there is increasing evidence that selection for resistant phenotypes is occurring in natural environments.

Agricultural use of antibiotics and the evolution and transfer of antibiotic-resistant bacteria.

  • G. Khachatourians
  • Biology
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
  • 1998
The author reviews trends in antibiotic use in animal husbandry and agriculture in general and particular aspects of resistance in bacterial species common to both the human population and the agrifood industry are emphasized.

Antibiotic uptake by plants from soil fertilized with animal manure.

The potential human health risks associated with consumption of fresh vegetables grown in soil amended with antibiotic laden manures may be higher for people who are allergic to antibiotics and there is also the possibility of enhanced antimicrobial resistance as a result of human consumption of these vegetables.

Resistance in the environment.

  • K. Kümmerer
  • Environmental Science
    The Journal of antimicrobial chemotherapy
  • 2004
The input of resistant bacteria into the environment seems to be an important source of resistance in the environment, and the effects of subinhibitory concentrations of antibiotics and disinfectants on environmental bacteria are questionable.

Effect of Length of Time before Incorporation on Survival of Pathogenic Bacteria Present in Livestock Wastes Applied to Agricultural Soil

It is indicated that not incorporating contaminated livestock wastes into soil is a potential intervention measure that may help to limit the spread of zoonotic agents further up the food chain.

Fate of veterinary antibiotics in a macroporous tile drained clay soil

It is evident that processes governing pesticide fate also apply to veterinary antibiotics, while preferential flow via desiccation cracks and worm channels to the tile drains was found to be the most important route for translocation of the chemicals.

The Potential Role of Concentrated Animal Feeding Operations in Infectious Disease Epidemics and Antibiotic Resistance

Concern about the risk of an influenza pandemic leads this working group to recommend that regulations be promulgated to restrict the co-location of swine and poultry concentrated animal feeding operations (CAFOs) on the same site and to set appropriate separation distances.