Fatal primary Epstein-Barr virus infection masquerading as histiocytic medullary reticulosis in young children in Taiwan.

@article{Su1990FatalPE,
  title={Fatal primary Epstein-Barr virus infection masquerading as histiocytic medullary reticulosis in young children in Taiwan.},
  author={I. J. Su and David T. Lin and Hung Chang Hsieh and Sun Hee Lee and J Y Chen and R L Chen and Chin Yun Lee},
  journal={Hematologic pathology},
  year={1990},
  volume={4 4},
  pages={189-95}
}
We reported 3 fatal cases of primary Epstein-Barr virus (EBV) infection resembling histiocytic medullary reticulosis (HMR) in young children in Taiwan, where an HMR-like illness has been previously found to be prevalent. The disease ran a fulminant course, manifesting as fever, anemia, jaundice, skin rash, pulmonary infiltration, and/or hepatosplenomegaly lasting for only 1-3 weeks. Laboratory tests revealed no hemolytic anemia and Coombs test was negative. Sepsis or HMR was the main clinical… CONTINUE READING

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