Fatal panniculitis.

  title={Fatal panniculitis.},
  author={Iris K. Aronson and Dennis P. West and Daina Variakojis and Frederick D Malkinson and H. Douglas Wilson and Howard Jerome Zeitz},
  journal={Journal of the American Academy of Dermatology},
  volume={12 3},
The Weber-Christian syndrome (relapsing nodular panniculitis) displays a clinical spectrum varying from short, self-limited, or intermittent disease episodes to persistent disease with fatal outcome. Inflamed adipose tissue is exclusively subcutaneous in some patients and is both subcutaneous and perivisceral in others. Inflammation of fat may induce a focal cutaneous or a systemic extracutaneous histiocytic proliferative response in which hemophagocytosis may be a frequent characteristic… CONTINUE READING