Fatal necrotizing pancreatitis caused by hepatitis B virus infection in a liver transplant recipient.

@article{Cavallari1995FatalNP,
  title={Fatal necrotizing pancreatitis caused by hepatitis B virus infection in a liver transplant recipient.},
  author={Antonino Cavallari and Marco Vivarelli and Antonia D'Errico and Roberto Bellusci and Paolo Scarani and E DeRaffele and Bruno Nardo and Giuseppe Gozzetti},
  journal={Journal of hepatology},
  year={1995},
  volume={22 6},
  pages={685-90}
}
A 32-year-old man who had undergone liver transplantation for fulminant hepatitis due to HBV infection developed fatal acute necrotizing pancreatitis on the 60th post-transplant day, while showing signs of intense viral replication. Immunohistochemistry and in situ hybridization of the pancreas following autopsy showed the presence of HBsAG and HBV-DNA in the cytoplasm of acinar cells, together with the picture of necrotizing pancreatitis. Clinical and histological features seem to indicate… CONTINUE READING