Fatal methyldopa-associated granulomatous hepatitis and myocarditis.

  • G H Bezahler
  • Published 1982 in The American journal of the medical sciences


A 78-year-old woman developed spiking fever of obscure etiology while receiving long term therapy with methyldopa and died suddenly seven days after admission to the hospital. Autopsy showed widespread granulomas in the liver, spleen, lymph nodes and bone marrow, interstitial myocarditis with granulomatous features and renovascular vasculitis. Eosinophils… (More)


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