Fatal invasive cerebral Absidia corymbifera infection following bone marrow transplantation

@article{Paterson2000FatalIC,
  title={Fatal invasive cerebral Absidia corymbifera infection following bone marrow transplantation},
  author={P E Paterson and S. Marshall and Bronwen E Shaw and J A Kendra and Mark Ethel and C Kibbler and H G Prentice and M S Potter},
  journal={Bone Marrow Transplantation},
  year={2000},
  volume={26},
  pages={701-703}
}
A 56-year-old dairy farmer received a fully HLA matched unrelated donor marrow transplant for high risk CML in chronic phase. His early post-transplant course was complicated by a series of massive intracerebral bleeds and by sepsis related to a malignant otitis externa. The microbial pathogen isolated from ear swabs was found to be Absidia corymbifera, but CT scan at the time showed no intracerebral extension. Despite neutrophil engraftment and aggressive antifungal management he succumbed… CONTINUE READING

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