Fatal disseminated BCG infection. An investigation of the immunodeficiency.

@article{Passwell1976FatalDB,
  title={Fatal disseminated BCG infection. An investigation of the immunodeficiency.},
  author={Justine Passwell and Doug Katz and Yitzchak Frank and Z Vi Spirer and Bernard E. Cohen and Micha Ziprkowski},
  journal={American journal of diseases of children},
  year={1976},
  volume={130 4},
  pages={433-6}
}
A 2-year-old boy had a fatal disseminated BCG infection. Immunologic assessment showed a normal humoral response and normal numbers of E rosettes, normal thymus weight and histological features, but an abnormal response of lymphocytes in vitro and negative skin tests. Histological examination showed the presence of Gram-negative acid-fast bacilli within the macrophages. The possible mechanisms of immunodeficiency in this patient are discussed.