Fatal diffuse alveolar damage associated with oxaliplatin administration.

  title={Fatal diffuse alveolar damage associated with oxaliplatin administration.},
  author={Jack L Watkins and Julian H Slade and A. Phan and Cathy Eng and Annikka Weissferdt and Michael James Overman},
  journal={Clinical colorectal cancer},
  volume={10 3},
Oxaliplatin-based chemotherapy regimens are currently a standard of care for the treatment of colorectal cancer in both the adjuvant and metastatic disease settings. Significant improvements in survival have resulted from the use of oxaliplatin-based combinations. This article describes the use of oxaliplatin-based chemotherapy in a patient with stage III colon cancer who developed fatal diffuse alveolar damage during his adjuvant therapy. Other cases of pulmonary toxicity associated with… CONTINUE READING