Fatal complications after stereotactic body radiation therapy for central lung tumors abutting the proximal bronchial tree.

@article{Haseltine2016FatalCA,
  title={Fatal complications after stereotactic body radiation therapy for central lung tumors abutting the proximal bronchial tree.},
  author={Justin M. Haseltine and Andreas Rimner and Daphna Y. Gelblum and Ankit Modh and Kenneth E. Rosenzweig and Andrew Jackson and Ellen D. Yorke and Abraham Jing-Ching Wu},
  journal={Practical radiation oncology},
  year={2016},
  volume={6 2},
  pages={e27-33}
}
PURPOSE Stereotactic body radiation therapy (SBRT) is associated with excess toxicity following treatment of central lung tumors. Risk-adapted fractionation appears to have mitigated this risk, but it remains unclear whether SBRT is safe for all tumors within the central lung zone, especially those abutting the proximal bronchial tree (PBT). We investigated the dependence of toxicity on tumor proximity to PBT and whether tumors abutting the PBT had greater toxicity than other central lung… CONTINUE READING
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