Fatal colitis in a hemophilic patient with inhibitor.

  title={Fatal colitis in a hemophilic patient with inhibitor.},
  author={Kenneth A. Schwartz and John A. Penner and R F Fekety and Robert W. Bailey},
  journal={Southern medical journal},
  volume={70 5},
A severe colitis developed in a hemophilic patient following an antibiotic regimen which included clindamycin. A surgical procedure, total hip replacement, had been complicated by the appearance of a powerful factor VIII inhibitor and a Bacteroides fragilis infection. The resulting bleeding diathesis was successfully managed with the use of an "activated… CONTINUE READING