Fat-induced changes in mouse pancreatic islet insulin secretion, insulin biosynthesis and glucose metabolism


Insulin secretion, insulin biosynthesis and islet glucose oxidation were studied in pancreatic islets isolated from fat-fed diabetic mice of both sexes. Insulin secretion from isolated islets was studied after consecutive stimulation with α-ketoisocaproic acid + glutamine, glucose, forskolin, and 12-O-tetradecanoylphorbol 13-acetate. Glucose-induced insulin… (More)
DOI: 10.1007/BF00778997


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