Fat grafting accelerates revascularisation and decreases fibrosis following thermal injury.

@article{Sultan2012FatGA,
  title={Fat grafting accelerates revascularisation and decreases fibrosis following thermal injury.},
  author={Steven M Sultan and Jason S Barr and Parag Butala and Edward H. Davidson and Andrew L. Weinstein and Denis Knobel and Pierre B. Saadeh and Stephen M. Warren and Sydney R. Coleman and Alexes Hazen},
  journal={Journal of plastic, reconstructive & aesthetic surgery : JPRAS},
  year={2012},
  volume={65 2},
  pages={219-27}
}
BACKGROUND Fat grafting has been shown clinically to improve the quality of burn scars. To date, no study has explored the mechanism of this effect. We aimed to do so by combining our murine model of fat grafting with a previously described murine model of thermal injury. METHODS Wild-type FVB mice (n=20) were anaesthetised, shaved and depilitated. Brass rods were heated to 100°C in a hot water bath before being applied to the dorsum of the mice for 10s, yielding a full-thickness injury… CONTINUE READING
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