Fat-free mass and its predictors in Huntington’s disease

@article{Sssmuth2015FatfreeMA,
  title={Fat-free mass and its predictors in Huntington’s disease},
  author={S. D. S{\"u}ssmuth and V M{\"u}ller and Carolin Geitner and G. B. Landwehrmeyer and Samuel Iff and Armin Gemperli and Michael Orth},
  journal={Journal of Neurology},
  year={2015},
  volume={262},
  pages={1533-1540}
}
The causes of weight loss in Huntington’s disease (HD) are not entirely clear. The aim was to identify risk factors that are associated with a loss of metabolically active tissues, i.e. fat-free mass. A consecutive cohort of non-diabetic HD participants (manifest HD, n = 43; CAG: mean 43.6.0 ± 3.6; preHD, n = 10; CAG: mean 41.4 ± 1.4) and 36 healthy controls was recruited. Twenty-five HD participants were early-stage HD (UHDRS Total Functional Capacity [TFC] stages I and II), 12 mid-stage HD… CONTINUE READING
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