Fat accumulation in Caenorhabditis elegans is mediated by SREBP homolog SBP-1

  title={Fat accumulation in Caenorhabditis elegans is mediated by SREBP homolog SBP-1},
  author={Toshihisa Nomura and Makoto Horikawa and Satoru Shimamura and Teppei Hashimoto and Kazuichi Sakamoto},
  journal={Genes & Nutrition},
Research into the metabolism of fats may reveal potential targets for developing pharmaceutical approaches to obesity and related disorders. Such research may be limited, however, by the cost and time involved in using mammalian subjects or developing suitable cell lines. To determine whether invertebrates could be used to carry out such research more efficiently, we investigated the ability of Caenorhabditis elegans (C. elegans) to accumulate body fat following the consumption of excess… CONTINUE READING
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