Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients

@article{Lee2011FastingVD,
  title={Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients},
  author={Ctd Lee and Valter D. Longo},
  journal={Oncogene},
  year={2011},
  volume={30},
  pages={3305-3316}
}
The dietary recommendation for cancer patients receiving chemotherapy, as described by the American Cancer Society, is to increase calorie and protein intake. Yet, in simple organisms, mice, and humans, fasting—no calorie intake—induces a wide range of changes associated with cellular protection, which would be difficult to achieve even with a cocktail of potent drugs. In mammals, the protective effect of fasting is mediated, in part, by an over 50% reduction in glucose and insulin-like growth… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 176 REFERENCES

Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

VIEW 15 EXCERPTS

The comparative physiology of food deprivation: from feast to famine.

VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Beziehungen zwischen Ernährung und Tumorwachstum

  • C. Moreschi
  • Z für Immunitätsforsch 2: 651–675.
  • 1909
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Resistance and augmentation of innate immunity in mice exposed to starvation.

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL