Fasting serum taurine-conjugated bile acids are elevated in type 2 diabetes and do not change with intensification of insulin.

@article{Wewalka2014FastingST,
  title={Fasting serum taurine-conjugated bile acids are elevated in type 2 diabetes and do not change with intensification of insulin.},
  author={Marlene Wewalka and M F Patti and Corinne Barbato and Sander M. Houten and Allison B. Goldfine},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2014},
  volume={99 4},
  pages={1442-51}
}
CONTEXT Bile acids (BAs) are newly recognized signaling molecules in glucose and energy homeostasis. Differences in BA profiles with type 2 diabetes mellitus (T2D) remain incompletely understood. OBJECTIVE The objective of the study was to assess serum BA composition in impaired glucose-tolerant, T2D, and normal glucose-tolerant persons and to monitor the effects of improving glycemia on serum BA composition in T2D patients. DESIGN AND SETTING This was a cross-sectional cohort study in a… CONTINUE READING
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Metabolite profiling identifies 1450 Wewalka et al Taurine-Conjugated Bile Acids and Glycemia

  • S Cheng, EP Rhee, MG Larson
  • J Clin Endocrinol Metab,
  • 2014
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