Fasting plasma glucose as a screening test for gestational diabetes mellitus

@article{Agarwal2006FastingPG,
  title={Fasting plasma glucose as a screening test for gestational diabetes mellitus},
  author={Mukesh M. Agarwal and Gurdeep Singh Dhatt},
  journal={Archives of Gynecology and Obstetrics},
  year={2006},
  volume={275},
  pages={81-87}
}
  • M. Agarwal, G. Dhatt
  • Published 15 January 2007
  • Medicine
  • Archives of Gynecology and Obstetrics
Although debated, most preeminent expert panels recommend routine screening for gestational diabetes mellitus (GDM). Among the many tests that have been used and evaluated for the screening of GDM, the fasting plasma glucose (FPG) remains very appealing. It is easy to administer, well tolerated, inexpensive, reproducible and patient friendly. However attractive, the FPG has given varied results in different populations and its use as a screening test for GDM remains uncertain. This review will… Expand
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TLDR
A study with high-risk outpatient pregnant women in the State University Hospital of Rio de Janeiro, Brazil conducted in 1994 determined an FPG value with good sensitivity and specificity that could identify pregnant women at risk for GDM. Expand
Gestational diabetes: fasting and postprandial glucose as first prenatal screening tests in a high-risk population.
TLDR
Though GDM could be diagnosed in > 40% women in early pregnancy at their first prenatal visit, the poor specificity and high FPR of FPG and PPG, alone or in combination, make them unsuitable screening tests for GDM. Expand
Screening for gestational diabetes in a high‐risk population using fasting plasma glucose
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  • Medicine
  • International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • 2000
TLDR
It is indicated that the fasting glucose alone would have eliminated the need for nearly 45% of the oGTTs with only 16 patients (3.7%) being misclassified. Expand
Gestational diabetes: utility of fasting plasma glucose as a screening test depends on the diagnostic criteria
Aims  To demonstrate the effect of diagnostic criteria, as defined by four international expert panels, on the usefulness of fasting plasma glucose (FPG) as a screening test for gestational diabetesExpand
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While it is not possible to issue a guideline for the best method of screening, the use of a 75 g OGTT instead of an OGCT as first line of testing for women from high risk populations will avoid theExpand
Gestational diabetes: problems associated with the oral glucose tolerance test.
TLDR
The United Arab Emirates is a multi-ethnic community with a very high prevalence of GDM and multi-parity resulting in a high percentage of pregnant women undergoing the diagnostic OGTT, and all other major expert panels like the World Health Organization continue to use it as the “gold-standard” for the diagnosis. Expand
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Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees that is first detected during pregnancy and provides a unique opportunity to study the early pathogenesis of diabetes and to develop interventions to prevent the disease. Expand
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TLDR
An elevated glucose loading test result was associated with but not highly predictive of gestational diabetes mellitus, and omission of the third-hour plasma glucose measurement of the glucose tolerance test alters the sensitivity of the test. Expand
Gestational diabetes in a high-risk population: using the fasting plasma glucose to simplify the diagnostic algorithm.
TLDR
Though the high false positive rate at any FPG threshold with adequate sensitivity makes the FPG an inappropriate test for GDM screening, the FGP has the potential to avoid nearly one-third of the cumbersome OGTTs at the expense of missing one-fifth of pregnant women with milder GDM. Expand
Could the fasting plasma glucose assay be used to screen for gestational diabetes?
TLDR
It is concluded that the fasting plasma glucose assay may perform better than the one-hour post-glucose test as a screening test for gestational diabetes. Expand
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