Fasting-mediated alteration studies in insulin action on lipolysis and lipogenesis in obese women.

@article{Arner1987FastingmediatedAS,
  title={Fasting-mediated alteration studies in insulin action on lipolysis and lipogenesis in obese women.},
  author={Peter Arner and Peter Engfeldt},
  journal={The American journal of physiology},
  year={1987},
  volume={253 2 Pt 1},
  pages={E193-201}
}
The effects of fasting on insulin-induced antilipolysis and lipogenesis were investigated in vitro in isolated human fat cells of 11 obese females. Glycerol release and lipogenesis were determined simultaneously in the same test tube and related to methylglucose transport and specific insulin binding. Insulin binding and sensitivity and the responsiveness (maximum effect) of insulin-induced antilipolysis were enhanced by fasting. The latter was strongly correlated with an enhancement in the… CONTINUE READING