Fasting-induced increases in food intake and neuropeptide Y gene expression are attenuated in aging male brown Norway rats.

@article{Gruenewald1996FastinginducedII,
  title={Fasting-induced increases in food intake and neuropeptide Y gene expression are attenuated in aging male brown Norway rats.},
  author={David A Gruenewald and Brett T. Marck and Alvin M. Matsumoto},
  journal={Endocrinology},
  year={1996},
  volume={137 10},
  pages={4460-7}
}
Aging in man is associated with alterations in food intake (FI) and body weight (BW). To establish a model of age-related alterations in FI and BW regulation, FI and BW were determined in young (3-month-old), middle-aged (12-month-old), and old (24-month-old) male Brown Norway rats during ad libitum feeding and after 72 h of fasting. FI was reduced with aging both during ad libitum feeding and after fasting. With fasting, young rats lost more BW than older rats, but regained BW more rapidly… CONTINUE READING

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