Fasting in mood disorders: neurobiology and effectiveness. A review of the literature

@article{Fond2013FastingIM,
  title={Fasting in mood disorders: neurobiology and effectiveness. A review of the literature},
  author={G. Fond and A. Macgregor and M. Leboyer and A. Michalsen},
  journal={Psychiatry Research},
  year={2013},
  volume={209},
  pages={253-258}
}
Clinicians have found that fasting was frequently accompanied by an increased level of vigilance and a mood improvement, a subjective feeling of well-being, and sometimes of euphoria. Therapeutic fasting, following an established protocol, is safe and well tolerated. We aim in this article to explore the biological mechanisms activated during fasting that could have an effect on brain function with particular focus on mood (we do not discuss here the mechanisms regulating eating behavior) and… Expand
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Additive antidepressant-like effects of fasting with imipramine via modulation of 5-HT2 receptors in the mice
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  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • 2014
TLDR
Results suggest that acute fasting produces antidepressant-like effects via enhancement of the p-CREB/CREB ratio, and additive antidepressant- like effects of fasting with imipramine may be related to modulating 5-HT2 receptors. Expand
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