Fasting hyperinsulinemia is a predictor of increased body weight gain and obesity in Pima Indian children.

@article{Odeleye1997FastingHI,
  title={Fasting hyperinsulinemia is a predictor of increased body weight gain and obesity in Pima Indian children.},
  author={O. E. Odeleye and Maximilian P. J. de Courten and David J. Pettitt and Eric Ravussin},
  journal={Diabetes},
  year={1997},
  volume={46 8},
  pages={1341-5}
}
Hyperinsulinemia is commonly associated with obesity, but it has not been determined which defect comes first. Some have proposed that hyperinsulinemia may precede obesity in populations prone to NIDDM, such as Pima Indians or Pacific Islanders. In contrast, longitudinal studies in adults show that insulin sensitivity and low fasting insulin concentrations are associated with increased weight gain, whereas insulin resistance seems to protect against weight gain. The present study examined… CONTINUE READING
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