Fasting hyperglycaemia and impaired oral glucose tolerance in acute Trypanosoma brucei infection of rats.


Trypanosoma brucei (Federe strain) produced all acute infection in rats given 10(6) parasites intraperitoneally. Parasitaemia, which first appeared at 2 days post-infection (pi), was heavy from day 5 until death at 8 to 12 days pi. The fasting tail-blood glucose (FBG) concentrations in the infected rats increased significantly (P<0.05) from 2.73+/-0.14 mmol… (More)


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