Fasting glucose homeostasis in the adaptation to chronic nutritional deprivation in rats.


The hormonal basis for the metabolic paradox of relative hypoglycemia despite insulinopenia and insulin resistance in chronic nutritional deprivation was studied in weanling rats restricted to 60% of ad libitum intake over 8 wk (n = 12 each). Lower insulin and glucagon levels were observed in both peripheral and portal blood (P = 0.0016) in the malnourished… (More)


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