Fasting Induces the Expression of PGC-1α and ERR Isoforms in the Outer Stripe of the Outer Medulla (OSOM) of the Mouse Kidney

@inproceedings{Teng2011FastingIT,
  title={Fasting Induces the Expression of PGC-1α and ERR Isoforms in the Outer Stripe of the Outer Medulla (OSOM) of the Mouse Kidney},
  author={Christina T. Teng and Yin Li and Pat S Stockton and Julie Foley},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Peroxisome proliferator-activated receptor-γ co-activator-1α (PGC-1α) is a member of the transcriptional coactivator family that plays a central role in the regulation of cellular energy metabolism under various physiological stimuli. During fasting, PGC-1α is induced in the liver and together with estrogen-related receptor a and γ (ERRα and ERRγ, orphan nuclear receptors with no known endogenous ligand, regulate sets of genes that participate in the energy balance program. We found… CONTINUE READING

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Trends Endocrinol Metab • 2008
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Highly Influenced

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