Faster in and faster out: accelerating insulin absorption and action by insulin infusion site warming.

@article{Cengiz2014FasterIA,
  title={Faster in and faster out: accelerating insulin absorption and action by insulin infusion site warming.},
  author={Eda Cengiz and Stuart Weinzimer and Jennifer L Sherr and Eileen M. Tichy and Lori R. Carria and Darryll Cappiello and Amy T. Steffen and William V Tamborlane},
  journal={Diabetes technology & therapeutics},
  year={2014},
  volume={16 1},
  pages={20-5}
}
OBJECTIVE This study was undertaken to investigate the effect of an insulin infusion site warming device, the InsuPatch(40)(™) (IP(40)) (InsuLine Medical Ltd., Petach-Tikvah, Israel), on insulin aspart pharmacodynamics (PD) and pharmacokinetics (PK) in adolescents with type 1 diabetes. SUBJECTS AND METHODS Seventeen subjects with type 1 diabetes (age, 15±1 years; hemoglobin A1c, 7.5±0.2% [58±2.2 mmol/mol]) underwent two euglycemic clamps performed on separate mornings with and without IP(40… CONTINUE READING

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