Fast wavelet based functional models for transcriptome analysis with tiling arrays.

@article{Clement2012FastWB,
  title={Fast wavelet based functional models for transcriptome analysis with tiling arrays.},
  author={Lieven Clement and Kristof De Beuf and Olivier Thas and Marnik Vuylsteke and Rafael A. Irizarry and Ciprian M. Crainiceanu},
  journal={Statistical applications in genetics and molecular biology},
  year={2012},
  volume={11 1},
  pages={Article 4}
}
For a better understanding of the biology of an organism, a complete description is needed of all regions of the genome that are actively transcribed. Tiling arrays are used for this purpose. They allow for the discovery of novel transcripts and the assessment of differential expression between two or more experimental conditions such as genotype, treatment, tissue, etc. In tiling array literature, many efforts are devoted to transcript discovery, whereas more recent developments also focus on… CONTINUE READING

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