Fast vs. slow exhalation before O2 inhalation alters subsequent phase III slope.

@article{Hurst1984FastVS,
  title={Fast vs. slow exhalation before O2 inhalation alters subsequent phase III slope.},
  author={Thomas S Hurst and Brian L. Graham and David J Cotton},
  journal={Journal of applied physiology: respiratory, environmental and exercise physiology},
  year={1984},
  volume={56 1},
  pages={52-6}
}
We studied 10 symptom-free lifetime non-smokers and 17 smokers all with normal pulmonary function studies. All subjects performed single-breath N2 washout tests by either exhaling slowly ("slow maneuver") from end inspiration (EI) to residual volume (RV) or exhaling maximally ("fast maneuver") from EI to RV. After either maneuver, subjects then slowly inhaled 100% O2 to total lung capacity (TLC) and without breath holding, exhaled slowly back to RV. In the nonsmokers seated upright phase III… CONTINUE READING