Fast targeted gene transfection and optogenetic modification of single neurons using femtosecond laser irradiation

Abstract

A prevailing problem in neuroscience is the fast and targeted delivery of DNA into selected neurons. The development of an appropriate methodology would enable the transfection of multiple genes into the same cell or different genes into different neighboring cells as well as rapid cell selective functionalization of neurons. Here, we show that optimized… (More)
DOI: 10.1038/srep03281

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