Fast-scanning AFM is now applicable to the analyses of single-molecule reactions in nano-biophysics

Abstract

Atomic force microscopy (AFM) has been used to visualize nano-scale structures of DNA, proteins and higher-order structures of DNA/protein complexes, such as chromatin and chromosome. Recently, there has been remarkable progress to visualize reaction dynamics at a single molecular level in real time and to measure a single molecular kinetics by using newly… (More)

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