Fast parametric imaging algorithm for dual-input biomedical system parameter estimation

@article{Choi2006FastPI,
  title={Fast parametric imaging algorithm for dual-input biomedical system parameter estimation},
  author={Hon-Chit Choi and Sirong Chen and David Dagan Feng and Koon-Pong Wong},
  journal={Computer methods and programs in biomedicine},
  year={2006},
  volume={81 1},
  pages={49-55}
}
Medical parametric imaging with dynamic positron emission tomography (PET) plays an increasingly potential role in modern biomedical research and clinical diagnosis. The key issue in parametric imaging is to estimate parameters based on sampled data at the pixel-by-pixel level from certain dynamic processes described by valid mathematical models. Classic nonlinear least squares (NLS) algorithm requires a "good" initial guess and the computational time-complexity is high, which is impractical… CONTINUE READING