Fast multislice mapping of the myelin water fraction using multicompartment analysis of T2* decay at 3T: a preliminary postmortem study.

@article{Du2007FastMM,
  title={Fast multislice mapping of the myelin water fraction using multicompartment analysis of T2* decay at 3T: a preliminary postmortem study.},
  author={Yiping P. Du and Renxin Chu and Dosik Hwang and Mark S. Brown and Bette K Kleinschmidt-DeMasters and Debra Singel and Jack Simon},
  journal={Magnetic resonance in medicine},
  year={2007},
  volume={58 5},
  pages={865-70}
}
Quantitative mapping of the myelin water content can provide significant insight into the pathophysiology of several white matter diseases, such as multiple sclerosis and leukoencephalopathies, and can potentially become a useful clinical tool for early diagnosis of these diseases. In this study, multicompartment analysis of T(2)(*) decay (MCAT(2)(*)) was used for the quantitative mapping of myelin water fraction (MWF). T(2)(*) decay of each voxel at multiple slice locations was acquired in… CONTINUE READING
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