Fast fluorescence laser tracking microrheometry, II: quantitative studies of cytoskeletal mechanotransduction.

@article{Jonas2008FastFL,
  title={Fast fluorescence laser tracking microrheometry, II: quantitative studies of cytoskeletal mechanotransduction.},
  author={Maxine Jonas and Hayden Huang and Roger D Kamm and Peter So},
  journal={Biophysical journal},
  year={2008},
  volume={95 2},
  pages={895-909}
}
Fluorescence laser tracking microrheometry (FLTM) is what we believe to be a novel method able to assess the local, frequency-dependent mechanical properties of living cells with nanometer spatial sensitivity at speeds up to 50 kHz. In an earlier article, we described the design, development, and optimization phases of the FLTM before reporting its performances in a variety of viscoelastic materials. In the work presented here, we demonstrate the suitability of FLTM to study local cellular… CONTINUE READING

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Cell morphology and migration linked to substrate rigidity

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