Fast dissolving paracetamol/caffeine nanofibers prepared by electrospinning.

Abstract

A series of polyvinylpyrrolidone fibers loaded with paracetamol (PCM) and caffeine (CAF) was fabricated by electrospinning and explored as potential oral fast-dissolving films. The fibers take the form of uniform cylinders with smooth surfaces, and contain the drugs in the amorphous form. Drug-polymer intermolecular interactions were evidenced by infrared… (More)
DOI: 10.1016/j.ijpharm.2014.10.036

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