Fast axonal transport is modulated by altering trans-axolemmal calcium flux.

@article{Breuer1992FastAT,
  title={Fast axonal transport is modulated by altering trans-axolemmal calcium flux.},
  author={Andrea Breuer and Meredith Bond and Mark Atkinson},
  journal={Cell calcium},
  year={1992},
  volume={13 4},
  pages={249-62}
}
Factors involved in fast axonal transport (motor proteins, microtubules, organelles, etc.) have been identified but the molecular mechanism controlling transport is unknown. We used video enhanced microscopy to directly evaluate the effect of calcium on fast axonal transport (FAxT). FAxT alterations included rapid speed decreases (within minutes) in Ca2+ free buffer and rapid speed increases (within seconds) when axons were treated with parathyroid hormone, BAY K 8644, or K+ depolarization. The… CONTINUE READING

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