Fast and Simple Detection of Yersinia pestis Applicable to Field Investigation of Plague Foci

  title={Fast and Simple Detection of Yersinia pestis Applicable to Field Investigation of Plague Foci},
  author={St{\'e}phanie Simon and Christian E. Demeure and Patricia Lamourette and Sofia Filali and Marc Charles Plaisance and Christophe Créminon and Herv{\'e} Volland and {\'E}lisabeth Carniel},
  journal={PLoS ONE},
Yersinia pestis, the plague bacillus, has a rodent-flea-rodent life cycle but can also persist in the environment for various periods of time. There is now a convenient and effective test (F1-dipstick) for the rapid identification of Y. pestis from human patient or rodent samples, but this test cannot be applied to environmental or flea materials because the F1 capsule is mostly produced at 37°C. The plasminogen activator (PLA), a key virulence factor encoded by a Y. pestis-specific plasmid, is… 

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