Fast ancestral gene order reconstruction of genomes with unequal gene content

@inproceedings{Feijo2016FastAG,
  title={Fast ancestral gene order reconstruction of genomes with unequal gene content},
  author={Pedro Feij{\~a}o and Eloi Araujo},
  booktitle={BMC Bioinformatics},
  year={2016}
}
During evolution, genomes are modified by large scale structural events, such as rearrangements, deletions or insertions of large blocks of DNA. Of particular interest, in order to better understand how this type of genomic evolution happens, is the reconstruction of ancestral genomes, given a phylogenetic tree with extant genomes at its leaves. One way of solving this problem is to assume a rearrangement model, such as Double Cut and Join (DCJ), and find a set of ancestral genomes that… CONTINUE READING

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