Fast Open-Source Toolkit for Water T2 Mapping in the Presence of Fat From Multi-Echo Spin-Echo Acquisitions for Muscle MRI

  title={Fast Open-Source Toolkit for Water T2 Mapping in the Presence of Fat From Multi-Echo Spin-Echo Acquisitions for Muscle MRI},
  author={Francesco Santini and Xeni Deligianni and Matteo Paoletti and Francesca Solazzo and Matthias Weigel and Paulo Loureiro de Sousa and Oliver Bieri and Mauro Monforte and Enzo Ricci and Giorgio Tasca and Anna Pichiecchio and Niels P Bergsland},
  journal={Frontiers in Neurology},
Imaging has become a valuable tool in the assessment of neuromuscular diseases, and, specifically, quantitative MR imaging provides robust biomarkers for the monitoring of disease progression. Quantitative evaluation of fat infiltration and quantification of the T2 values of the muscular tissue's water component (wT2) are two of the most essential indicators currently used. As each voxel of the image can contain both water and fat, a two-component model for the estimation of wT2 must be used… 

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